Cosmetics. Analytical methods. Measurement of traces of heavy metals in cosmetic finished products using ICP/MS technique (ISO 21392:2021, Corrected version 2021-12)
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This document provides a method for quantification of trace levels of heavy metals in cosmetic products. This document refers only to chromium, cobalt, nickel, arsenic, cadmium, antimony and lead. The methodology can apply to other elements, however, it is the responsibility of the analyst to demonstrate that it fits that purpose.
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Sisällysluettelo
Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Principle
5 Reagents
6 Apparatus and equipment
7 Preparation of standards solutions
7.1 General
7.2 Diluted nitric acid
7.3 Diluting solution
7.4 Internal standard solutions
7.5 Standard solutions
7.6 Calibration blank solution
7.7 Calibration solutions
8 Procedure
8.1 Preparation of samples
8.2 Pressure assisted digestion
8.3 Inductively coupled plasma mass spectrometry
8.4 Quality control of the analysis
9 Calculation
10 Method performance
11 Test report
Annex A Performance of the method determined by the accuracy profile methodology (informative)
Annex B Evaluation of the method via ISO 5725 statistical approach (informative)